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Epi 1:10,000
Class: Sympathomimetic
MOA: Alpha 1, Beta 1, Beat 2 stimulation
Indications: Cardiac Arrest; Anaphylaxis; Bradycardia
Contraindications: None in emergency setting
Side Effects: Palpitations; Anxiety; N&V
Onset/Duration: Immediate / 10 min
Route: IV, IO, IM Drip, ET
Considerations: Pregnancy Class “C” drug
Dose:
Adult
Cardiac Arrest: 1mg IVP every 3-5 min Anaphylaxis: 0.3-0.5 mg IVP Bradycardia: 2-10 mcg/kg PEDS
Cardiac Arrest: 0.01 mg/kg IVP every 3-5 minSupplied: 1mg/ 10mL
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Adenosine (Adenocard)
Class: Antiarrhythmic
MOA: Works by interrupting re-entry pathways
trough the AV nodes, slowing AV conduction causing refractory period to prolong.
Indications: SVT
Contraindications: Allergy
Side Effects: Bradycardia; Asystole; Facial Flushing;
CP; Light-headedness
Onset/Duration: Immediate / 12 seconds
Route: IV
Considerations: Elevate arm, rapid IVP in most central
site followed by 20 mL flush.
Be careful in patients who have Wolf
Parkinson's White (WPW)
Dose:
Adult: 6mg --> 12mg (only if ineffective after 2 min)
PEDS: 0.1
mg/kg (MAX 6mg), if ineffective, then 0.2 mgkg
(MAX 12 mg)
Supplied: 6mg/ 1mL ampules
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Amiodarone (Cordarone)
Class: Antiarrhythmic (Potassium Channel
Blocker)
MOA: Blocks the potassium channels, in doing
so it delays the hearts ability to repolarize. This will prolong the QT interval on the ECG/EKG.
Indications: VTACH with a Pulse; VTACH without a
Pulse; VFIB
Contraindications: Allergy; Bradycardia; AV Blocks
Side Effects: Allergic reaction; Bradycardia; AV Blocks
Onset/Duration: Immediate / 40 days (half life)
Route: IV; IO
Considerations: Get 12-lead before, to determine VTACH
Dose:
Adult:
VTACH + Pulse: 150mg IV given over 10 minutes
VTACH – Pulse: 300mg IVP à (after 5 min) 150mg
IVP
VFIB: 300mg
IVP à (after 5 min) 150mg IVP
PEDS:
VTACH + Pulse: 5mg/kg IV given over 20 minutes
VTACH – Pulse: 5mg/kg IVP
VFIB: 5mg/kg
IVP
Supplied: 150mg vials & 150mg/ 3mL
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